TY - JOUR
T1 - Efficient Encapsulation of Fluorinated Drugs in the Confined Space of Water-Dispersible Fluorous Supraparticles
AU - Pigliacelli, Claudia
AU - Maiolo, Daniele
AU - Nonappa, Nonappa
AU - Haataja, Johannes S.
AU - Amenitsch, Heinz
AU - Michelet, Claire
AU - Sánchez Moreno, Paola
AU - Tirotta, Ilaria
AU - Metrangolo, Pierangelo
AU - Baldelli Bombelli, Francesca
PY - 2017/12/18
Y1 - 2017/12/18
N2 - Fluorophobic-driven assemblies of gold nanomaterials were stabilized into water-dispersible fluorous supraparticles by the film-forming protein hydrophobin II. The strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport of high loadings of partially fluorinated drug molecules in water.
AB - Fluorophobic-driven assemblies of gold nanomaterials were stabilized into water-dispersible fluorous supraparticles by the film-forming protein hydrophobin II. The strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport of high loadings of partially fluorinated drug molecules in water.
KW - fluorous surfaces
KW - gold nanoparticles
KW - hydrophobin
KW - self-assembly
KW - supraparticles
UR - http://www.scopus.com/inward/record.url?scp=85034844711&partnerID=8YFLogxK
U2 - 10.1002/anie.201710230
DO - 10.1002/anie.201710230
M3 - Article
AN - SCOPUS:85034844711
SN - 1433-7851
VL - 56
SP - 16186
EP - 16190
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 51
ER -