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Abstract
Poly(2-oxazoline) networks with varying swelling degrees and varying hydrophilicity can be synthesized from 2-ethyl-2-oxazoline, 2-nonyl-2-oxazoline, 2-9’-decenyl-2-oxazoline and 2,2’-tetramethylene-bis-2-oxazoline in one-pot/one-step strategies. These gels can be loaded with organic molecules, such as fluorescein isothiocyanate, either during the polymerization (covalent attachment of the dye) or according to post-synthetic swelling/deswelling strategies (physical inclusion of the dye). Surface functionalization of ground gels by thiol-ene reactions with cysteine-bearing peptides exhibiting the arginine-glycine-aspartic acid (RGD) motif yields microparticles with enhanced recognition of human cancer cells compared to healthy endothelial cells.
Originalsprache | englisch |
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Seiten (von - bis) | 264-279 |
Fachzeitschrift | Polymers |
Jahrgang | 6 |
Ausgabenummer | 2 |
DOIs | |
Publikationsstatus | Veröffentlicht - 2014 |
Fields of Expertise
- Advanced Materials Science
Treatment code (Nähere Zuordnung)
- Basic - Fundamental (Grundlagenforschung)
- Experimental
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Synthetic approaches towards functional polymers
Mühlbacher, I., Kelly, A. M., Stelzer, F. & Wiesbrock, F.
1/01/10 → 31/12/13
Projekt: Forschungsprojekt