Abstract
Gene therapy is highly suited for prostate cancer (PC). Metal-organic-frameworks (MOFs) are potential gene delivery systems. Target-specific cytoplasmic and nuclear knockdown in host gene expression using ZIF-C is shown for the first time through RNAi and CRISPR/Cas9 based gene editing in PC cells. A green tea phytochemical coating enhances intracellular delivery.
Originalsprache | englisch |
---|---|
Seiten (von - bis) | 15406-15409 |
Seitenumfang | 4 |
Fachzeitschrift | Chemical Communications |
Jahrgang | 56 |
Ausgabenummer | 98 |
DOIs | |
Publikationsstatus | Veröffentlicht - 21 Dez. 2020 |
ASJC Scopus subject areas
- Keramische und Verbundwerkstoffe
- Chemie (insg.)
- Werkstoffchemie