Experimental investigation of the biomechanical response and the microstructure of the ventricular myocardium

Activity: Talk or presentationInvited talk at conference or symposiumScience to science


In this talk, current experimental approaches to determine mechanical properties and the microstructure of myocardial tissues will be presented. Most studies in the past utilized equibiaxial extension tests on hearts from animals. For myocardial tissues, however, these tests do not yield sufficient quantitative information to formulate a reliable constitutive law. In fact, such data may even suggest that the material is transversely isotropic. Myocardial tissue behaves mechanically orthotropic, which has been demonstrated by the results of simple shear tests in different directions on the passive ventricular myocardium from porcine hearts [3]. Moreover, myocardial tissues undergo complex patterns of tensile, compressive, and, in particular, shear deformations throughout the cardiac cycle. Prerequisites to capture the direction-dependent nonlinear material response involve a combination of biaxial extension test data with different loading protocols, and shear test data at different specimen orientations [4].
Period8 Jul 201812 Jul 2018
Event title8th World congress of Biomechanics
Event typeConference
LocationDublin, IrelandShow on map