Optimization of Pulsed Chemical Exchange Saturation Transfer MRI by Optimal Control

Activity: Talk or presentationTalk at conference or symposiumScience to science


We optimized CEST saturation pulse train using an optimal control framework and validated the simulation results on a preclinical scanner that allowed also Gold Standard continuous wave saturation. The optimized pulses almost reached the same saturation as the continuous wave pulse while addressing the allowed duty cycle and SAR limitations of clinical scanners. In measurements, the optimized pulses outperform state-of-the-art Gaussian pulses by over 47%.
Event titleJoint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting: ISMRM 2022
Event typeConference
LocationLondon, United KingdomShow on map
Degree of RecognitionInternational