Performance of Multipool-Lorentzian fitting for CEST-MRI using joint spatial regularization

  • Huemer, M. (Speaker)
  • Oliver Maier (Contributor)
  • Moritz Fabian (Contributor)
  • Kristian Bredies (Contributor)
  • Moritz Zaiss (Contributor)
  • Stollberger, R. (Contributor)

Activity: Talk or presentationPoster presentationScience to science


This work investigates an improved quantification algorithm for CEST spectra using a joint Frobenuis Total Generalized Variation (TGV) regularization. The performance is assessed with simulations, phantom and in-vivo measurement with respect to systematic errors and robustness. For comparison a pixel-wise fit using the Levenberg-Marquardt algorithm and the IDEAL algorithm were implemented. The TGV algorithm show the best performance in parameter fitting stability and parameter map SNR.
Period6 Jun 2023
Event titleISMRM & ISMRT Annual Meeting & Exhibition 2023
Event typeConference
LocationToronto, CanadaShow on map
Degree of RecognitionInternational