A critical appraisal of recent research in multi-domain indoor-environmental exposure

The insufficient availability of evidence-based guidance in practical treatment of multi-domain exposure situations in indoor environments has motivated multiple efforts to conceive and conduct studies on the combined effects of multiple factors on occupants' perception and evaluation of indoor-environmental quality. However, the research strategies that are being currently considered and in part implemented for this purpose may be subject to certain simplifications and misconceptions that would limit their ultimate conclusiveness and utility. The present discussion intends to highlight a number of such issues and encourage thus efforts toward a more robust framework for conducting research and developing standards regarding multi-domain exposure patterns in indoor environments and their implications for occupants' health and comfort