A Novel Way to Measure and Predict Development: A Heuristic Approach to Facilitate the Early Detection of Neurodevelopmental Disorders

BEE-PRI Study Group; Peter B Marschik; Florian B Pokorny; Robert Peharz; Dajie Zhang; Jonathan O'Muircheartaigh; Herbert Roeyers; Sven Bölte; Alicia J Spittle; Berndt Urlesberger; Björn Schuller; Luise Poustka; Sally Ozonoff; Franz Pernkopf; Thomas Pock; Kristiina Tammimies; Christian Enzinger; Magdalena Krieber; Iris Tomantschger; Katrin D Bartl-Pokorny; Jeff Sigafoos; Laura Roche; Gianluca Esposito; Markus Gugatschka; Karin Nielsen-Saines; Christa Einspieler; Walter E Kaufmann

doi:10.1007/s11910-017-0748-8

A Novel Way to Measure and Predict Development: A Heuristic Approach to Facilitate the Early Detection of Neurodevelopmental Disorders

BEE-PRI Study Group, Peter B Marschik^*, Florian B Pokorny, Robert Peharz, Dajie Zhang, Jonathan O'Muircheartaigh, Herbert Roeyers, Sven Bölte, Alicia J Spittle, Berndt Urlesberger, Björn Schuller, Luise Poustka, Sally Ozonoff, Franz Pernkopf, Thomas Pock, Kristiina Tammimies, Christian Enzinger, Magdalena Krieber, Iris Tomantschger, Katrin D Bartl-PokornyJeff Sigafoos, Laura Roche, Gianluca Esposito, Markus Gugatschka, Karin Nielsen-Saines, Christa Einspieler, Walter E Kaufmann

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE OF REVIEW: Substantial research exists focusing on the various aspects and domains of early human development. However, there is a clear blind spot in early postnatal development when dealing with neurodevelopmental disorders, especially those that manifest themselves clinically only in late infancy or even in childhood.

RECENT FINDINGS: This early developmental period may represent an important timeframe to study these disorders but has historically received far less research attention. We believe that only a comprehensive interdisciplinary approach will enable us to detect and delineate specific parameters for specific neurodevelopmental disorders at a very early age to improve early detection/diagnosis, enable prospective studies and eventually facilitate randomised trials of early intervention. In this article, we propose a dynamic framework for characterising neurofunctional biomarkers associated with specific disorders in the development of infants and children. We have named this automated detection 'Fingerprint Model', suggesting one possible approach to accurately and early identify neurodevelopmental disorders.

Original language	English
Pages (from-to)	43
Journal	Current Neurology and Neuroscience Reports
Volume	17
Issue number	5
DOIs	https://doi.org/10.1007/s11910-017-0748-8
Publication status	Published - May 2017

Keywords

Biomarkers
Early Diagnosis
Humans
Neurodevelopmental Disorders/diagnosis

Cooperations

BioTechMed-Graz

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10.1007/s11910-017-0748-8Licence: CC BY 4.0

Cite this

BEE-PRI Study Group, Marschik, P. B., Pokorny, F. B., Peharz, R., Zhang, D., O'Muircheartaigh, J., Roeyers, H., Bölte, S., Spittle, A. J., Urlesberger, B., Schuller, B., Poustka, L., Ozonoff, S., Pernkopf, F., Pock, T., Tammimies, K., Enzinger, C., Krieber, M., Tomantschger, I., ... Kaufmann, W. E. (2017). A Novel Way to Measure and Predict Development: A Heuristic Approach to Facilitate the Early Detection of Neurodevelopmental Disorders. Current Neurology and Neuroscience Reports , 17(5), 43. https://doi.org/10.1007/s11910-017-0748-8

BEE-PRI Study Group, Marschik, PB, Pokorny, FB, Peharz, R, Zhang, D, O'Muircheartaigh, J, Roeyers, H, Bölte, S, Spittle, AJ, Urlesberger, B, Schuller, B, Poustka, L, Ozonoff, S, Pernkopf, F , Pock, T, Tammimies, K, Enzinger, C, Krieber, M, Tomantschger, I, Bartl-Pokorny, KD, Sigafoos, J, Roche, L, Esposito, G, Gugatschka, M, Nielsen-Saines, K, Einspieler, C & Kaufmann, WE 2017, 'A Novel Way to Measure and Predict Development: A Heuristic Approach to Facilitate the Early Detection of Neurodevelopmental Disorders', Current Neurology and Neuroscience Reports , vol. 17, no. 5, pp. 43. https://doi.org/10.1007/s11910-017-0748-8

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AU - Tomantschger, Iris

AU - Bartl-Pokorny, Katrin D

AU - Sigafoos, Jeff

AU - Roche, Laura

AU - Esposito, Gianluca

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