A Tamper-Proof Audit and Control-System for the Doctor in the Loop

Peter Kieseberg, Bernd Malle, Peter Frühwirt, Edgar Weippl, Andreas Holzinger

Research output: Contribution to journalArticlepeer-review


The “doctor in the loop” is a new paradigm in information-driven medicine, picturing the doctor as authority inside a loop supplying an expert system with information on actual patients, treatment results, and possible additional (side-)effects, including general information in order to enhance data-driven medical science, as well as giving back treatment advice to the doctor himself. While this approach can be very beneficial for new medical approaches like P4 medicine (personal, predictive, preventive, and participatory), it also relies heavily on the authenticity of the data and thus increases the need for secure and reliable databases. In this paper, we propose a solution in order to protect the doctor in the loop against responsibility derived from manipulated data, thus enabling this new paradigm to gain acceptance in the medical community
Original languageEnglish
Pages (from-to)269-279
JournalBrain Informatics
Issue number4
Publication statusPublished - 15 Nov 2016


  • digital forensics
  • manipulation detection
  • data-driven science
  • P4 medicine
  • data science

ASJC Scopus subject areas

  • Information Systems

Fields of Expertise

  • Information, Communication & Computing

Treatment code (Nähere Zuordnung)

  • Basic - Fundamental (Grundlagenforschung)


Dive into the research topics of 'A Tamper-Proof Audit and Control-System for the Doctor in the Loop'. Together they form a unique fingerprint.

Cite this