Abstract
Currently unused black box optimization algorithms are compared against two popular self-optimization methods, the Nelder-Mead algorithm and the SNOBFIT method. Using various test problems and a real-life continuous flow Suzuki-Miyaura coupling reaction, two promising methods which surpassed the predominant methods in terms of reliability and speed of convergence were identified.
Original language | English |
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Article number | e202100091 |
Journal | Chemistry Methods |
Volume | 2 |
Issue number | 5 |
DOIs | |
Publication status | Published - 15 Feb 2022 |
Keywords
- flow chemistry
- self-optimization
- automation
- algorithms