Degradation of ZIF-8 in phosphate buffered saline media

Miriam De J. Velásquez-Hernández; Raffaele Ricco; Francesco Carraro; F. Ted Limpoco; Mercedes Linares-Moreau; Erich Leitner; Helmar Wiltsche; Johannes Rattenberger; Hartmuth Schröttner; Philipp Frühwirt; Eduard M. Stadler; Georg Gescheidt; Heinz Amenitsch; Christian J. Doonan; Paolo Falcaro

doi:10.1039/c9ce00757a

Degradation of ZIF-8 in phosphate buffered saline media

Miriam De J. Velásquez-Hernández, Raffaele Ricco, Francesco Carraro, F. Ted Limpoco, Mercedes Linares-Moreau, Erich Leitner, Helmar Wiltsche, Johannes Rattenberger, Hartmuth Schröttner, Philipp Frühwirt, Eduard M. Stadler, Georg Gescheidt, Heinz Amenitsch, Christian J. Doonan^*, Paolo Falcaro

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Understanding the stability of zeolitic imidazolate framework-8 (ZIF-8) under physiological conditions is critical in biotechnology and biomedicine for biosensing, biocatalysis, and drug delivery. The use of ZIF-8 has shown that this metal organic framework (MOF) and its derived bio-composites can degrade in presence of buffer solutions. Here we present an in-depth analysis of the structural and chemical changes of pure ZIF-8 particles exposed to phosphate buffered saline (PBS) media. Two different particle sizes (2 μm and 250 nm) were selected and the decomposition operated by 10 mM PBS (aka 1X) was studied using powder X-ray diffraction (PXRD), Fourier transformed infrared spectroscopy (FTIR), time resolved atomic force microscopy (AFM), in situ small angle X-ray scattering (SAXS), and ³¹P NMR.

Original language	English
Article number	21 (31)
Pages (from-to)	4538-4544
Number of pages	7
Journal	CrystEngComm
Volume	21
Issue number	31
DOIs	https://doi.org/10.1039/c9ce00757a
Publication status	Published - 2019

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

Access to Document

10.1039/c9ce00757aLicence: CC BY 4.0

Cite this

Velásquez-Hernández, M. D. J., Ricco, R., Carraro, F., Limpoco, F. T., Linares-Moreau, M., Leitner, E., Wiltsche, H., Rattenberger, J., Schröttner, H., Frühwirt, P., Stadler, E. M., Gescheidt, G., Amenitsch, H., Doonan, C. J., & Falcaro, P. (2019). Degradation of ZIF-8 in phosphate buffered saline media. CrystEngComm , 21(31), 4538-4544. Article 21 (31). https://doi.org/10.1039/c9ce00757a

Velásquez-Hernández, MDJ, Ricco, R, Carraro, F, Limpoco, FT, Linares-Moreau, M, Leitner, E, Wiltsche, H , Rattenberger, J , Schröttner, H, Frühwirt, P, Stadler, EM, Gescheidt, G , Amenitsch, H, Doonan, CJ & Falcaro, P 2019, 'Degradation of ZIF-8 in phosphate buffered saline media', CrystEngComm , vol. 21, no. 31, 21 (31), pp. 4538-4544. https://doi.org/10.1039/c9ce00757a

@article{62d9df48b3c44c0a84ce330109c5f90b,

title = "Degradation of ZIF-8 in phosphate buffered saline media",

abstract = "Understanding the stability of zeolitic imidazolate framework-8 (ZIF-8) under physiological conditions is critical in biotechnology and biomedicine for biosensing, biocatalysis, and drug delivery. The use of ZIF-8 has shown that this metal organic framework (MOF) and its derived bio-composites can degrade in presence of buffer solutions. Here we present an in-depth analysis of the structural and chemical changes of pure ZIF-8 particles exposed to phosphate buffered saline (PBS) media. Two different particle sizes (2 μm and 250 nm) were selected and the decomposition operated by 10 mM PBS (aka 1X) was studied using powder X-ray diffraction (PXRD), Fourier transformed infrared spectroscopy (FTIR), time resolved atomic force microscopy (AFM), in situ small angle X-ray scattering (SAXS), and 31P NMR.",

author = "Vel{\'a}squez-Hern{\'a}ndez, {Miriam De J.} and Raffaele Ricco and Francesco Carraro and Limpoco, {F. Ted} and Mercedes Linares-Moreau and Erich Leitner and Helmar Wiltsche and Johannes Rattenberger and Hartmuth Schr{\"o}ttner and Philipp Fr{\"u}hwirt and Stadler, {Eduard M.} and Georg Gescheidt and Heinz Amenitsch and Doonan, {Christian J.} and Paolo Falcaro",

year = "2019",

doi = "10.1039/c9ce00757a",

language = "English",

volume = "21",

pages = "4538--4544",

journal = "CrystEngComm ",

issn = "1466-8033",

publisher = "Royal Society of Chemistry",

number = "31",

}

TY - JOUR

T1 - Degradation of ZIF-8 in phosphate buffered saline media

AU - Velásquez-Hernández, Miriam De J.

AU - Ricco, Raffaele

AU - Carraro, Francesco

AU - Limpoco, F. Ted

AU - Linares-Moreau, Mercedes

AU - Leitner, Erich

AU - Wiltsche, Helmar

AU - Rattenberger, Johannes

AU - Schröttner, Hartmuth

AU - Frühwirt, Philipp

AU - Stadler, Eduard M.

AU - Gescheidt, Georg

AU - Amenitsch, Heinz

AU - Doonan, Christian J.

AU - Falcaro, Paolo

PY - 2019

Y1 - 2019

N2 - Understanding the stability of zeolitic imidazolate framework-8 (ZIF-8) under physiological conditions is critical in biotechnology and biomedicine for biosensing, biocatalysis, and drug delivery. The use of ZIF-8 has shown that this metal organic framework (MOF) and its derived bio-composites can degrade in presence of buffer solutions. Here we present an in-depth analysis of the structural and chemical changes of pure ZIF-8 particles exposed to phosphate buffered saline (PBS) media. Two different particle sizes (2 μm and 250 nm) were selected and the decomposition operated by 10 mM PBS (aka 1X) was studied using powder X-ray diffraction (PXRD), Fourier transformed infrared spectroscopy (FTIR), time resolved atomic force microscopy (AFM), in situ small angle X-ray scattering (SAXS), and 31P NMR.

AB - Understanding the stability of zeolitic imidazolate framework-8 (ZIF-8) under physiological conditions is critical in biotechnology and biomedicine for biosensing, biocatalysis, and drug delivery. The use of ZIF-8 has shown that this metal organic framework (MOF) and its derived bio-composites can degrade in presence of buffer solutions. Here we present an in-depth analysis of the structural and chemical changes of pure ZIF-8 particles exposed to phosphate buffered saline (PBS) media. Two different particle sizes (2 μm and 250 nm) were selected and the decomposition operated by 10 mM PBS (aka 1X) was studied using powder X-ray diffraction (PXRD), Fourier transformed infrared spectroscopy (FTIR), time resolved atomic force microscopy (AFM), in situ small angle X-ray scattering (SAXS), and 31P NMR.

UR - http://www.scopus.com/inward/record.url?scp=85070316319&partnerID=8YFLogxK

U2 - 10.1039/c9ce00757a

DO - 10.1039/c9ce00757a

M3 - Article

AN - SCOPUS:85070316319

SN - 1466-8033

VL - 21

SP - 4538

EP - 4544

JO - CrystEngComm

JF - CrystEngComm

IS - 31

M1 - 21 (31)

ER -

Degradation of ZIF-8 in phosphate buffered saline media

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this