Point/counterpoint: We should not take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification

Kyriaki Kostoglou, David M. Simpson, Stephen J. Payne*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

Abstract

Over the past years, a wide range of studies have provided evidence of asymmetry in the response of static and dynamic cerebral autoregulation (CA) during increasing and decreasing pressure challenges. The main message is that CA is stronger during transient increases of arterial blood pressure rather than decreases. Here we do not argue against the presence of CA asymmetry but we seek to raise questions regarding the measurement of the effect and whether this effect needs to be taken into account, especially in clinical settings.

Original languageEnglish
Pages (from-to)2354-2356
Number of pages3
JournalJournal of Cerebral Blood Flow and Metabolism
Volume42
Issue number12
Early online date13 Sept 2022
DOIs
Publication statusPublished - Dec 2022

Keywords

  • Asymmetry
  • cerebral autoregulation
  • cerebral blood flow
  • cerebral haemodynamics
  • transcranial Doppler

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Cardiology and Cardiovascular Medicine

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