(R)-selective hydroxynitrile lyase variants with a cupin fold having improved substrate scope and the use thereof

ROMANA WIEDNER,; KERSTIN STEINER,; Anton Glieder; HELMUT SCHWAB

(R)-selective hydroxynitrile lyase variants with a cupin fold having improved substrate scope and the use thereof

ROMANA WIEDNER, (Inventor), KERSTIN STEINER, (Inventor), Anton Glieder (Inventor), HELMUT SCHWAB (Inventor)

Research output: Patent

Abstract

The present invention relates to an improved recombinant cupin-hydroxynitrile lyase (HNL), which is capable to catalyze the asymmetric cyanohydrin reaction, wherein the recombinant cupin-HNL comprises at least one amino acid substitution, preferably at least three substitutions.

Translated title of the contribution	(R)-selective Hydroxynitrillyasevarianten mit einer Cupin-Faltung mit verbessertem Substratumfang, und Verwendung davon
Original language	English
Patent number	EP2955225
IPC	C12P 13/ 00 A I
Priority date	12/06/14
Publication status	Published - 16 Dec 2015

Cite this

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title = "(R)-selective hydroxynitrile lyase variants with a cupin fold having improved substrate scope and the use thereof",

abstract = "The present invention relates to an improved recombinant cupin-hydroxynitrile lyase (HNL), which is capable to catalyze the asymmetric cyanohydrin reaction, wherein the recombinant cupin-HNL comprises at least one amino acid substitution, preferably at least three substitutions.",

author = "ROMANA WIEDNER, and KERSTIN STEINER, and Anton Glieder and HELMUT SCHWAB",

year = "2015",

month = dec,

day = "16",

language = "English",

type = "Patent",

note = "EP2955225; C12P 13/ 00 A I",

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T1 - (R)-selective hydroxynitrile lyase variants with a cupin fold having improved substrate scope and the use thereof

AU - WIEDNER,, ROMANA

AU - STEINER,, KERSTIN

AU - Glieder, Anton

AU - SCHWAB, HELMUT

PY - 2015/12/16

Y1 - 2015/12/16

N2 - The present invention relates to an improved recombinant cupin-hydroxynitrile lyase (HNL), which is capable to catalyze the asymmetric cyanohydrin reaction, wherein the recombinant cupin-HNL comprises at least one amino acid substitution, preferably at least three substitutions.

AB - The present invention relates to an improved recombinant cupin-hydroxynitrile lyase (HNL), which is capable to catalyze the asymmetric cyanohydrin reaction, wherein the recombinant cupin-HNL comprises at least one amino acid substitution, preferably at least three substitutions.

M3 - Patent

M1 - EP2955225

ER -