Synthesis and Characterization of 3-Aminopropyl-phenyl Germanes

Christoph Garstenauer, Roland C. Fischer, Ana Torvisco*, Frank Uhlig

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Novel synthetic pathways for different 3-aminopropyl germanes are shown in this work. For this purpose, in Synthetic Route A, a corresponding germanium compound was metalated and, via salt metathesis, the corresponding protected 3-aminopropyl germane was formed. After the deprotection, the corresponding amino hydrochlorides were isolated. After a neutralization reaction, the 3-aminopropyl germanes were formed. With 3-aminopropyl-diphenyl-germanium hydride, (H2N(CH2)3)Ph2GeH, a new bifunctional building block was isolated. To form the corresponding 3-aminopropyl‑chloro germanes ((CyHN(CH2)3)Ph2GeCl and (H2N(CH2)3)Ph2GeCl), diphenyl‑chloro germane was used in a hydrogermylation to form the corresponding amines (Synthetic Route B). All compounds were characterized by state-of-the-art techniques, including single crystal X-ray diffraction for selected compounds.

Original languageEnglish
Article number122709
Number of pages10
JournalJournal of Organometallic Chemistry
Volume993
Early online date7 Apr 2023
DOIs
Publication statusPublished - 1 Jul 2023

Keywords

  • 3-aminopropyl germanes
  • 3-aminopropyl‑chloro germanes
  • Bifunctional germanes
  • Chloro germanes
  • Hydrogermylation

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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