Abstract
Manufacturing solid low-dose pharmaceutical products has always the homogeneity challenge. In continuous manufacturing, there is the additional challenge of feeding active pharmaceutical ingredient (API) dry powder at low rates. This paper presents a method for feeding API particles into a continuous extrusion process using a suspension. The challenges for feeding and the product homogeneity are both addressed.
Originalsprache | englisch |
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Seiten (von - bis) | 1360-1364 |
Seitenumfang | 4 |
Fachzeitschrift | Drug Development and Industrial Pharmacy |
Jahrgang | 42 |
Ausgabenummer | 8 |
DOIs | |
Publikationsstatus | Veröffentlicht - 2 Aug. 2016 |