Micro-Computed Tomography (µCT) as a Tool for High-Resolution 3D Imaging and Analysis of Intraocular Lenses: Feasibility and Proof of the Methodology to Evaluate YAG Pits

Andreas Borkenstein*, Eva-Maria Borkenstein, Fabio Eduardo Machado Charry, Harald Matthias Fitzek, Johannes Rattenberger, Robert Schennach, Gerald Kothleitner

*Korrespondierende/r Autor/-in für diese Arbeit

Publikation: Beitrag in einer FachzeitschriftArtikelBegutachtung

Abstract

Introduction

Posterior capsule opacification (PCO) is the most frequent late sequelae after successful cataract surgery. Neodymium:yttrium aluminum garnet (Nd:YAG) laser capsulotomy is considered the gold standard and a well-accepted, safe, and effective measure in treating PCO. However, iatrogenic damage of the intraocular lens (IOL) due to inappropriate focusing is a quite common side effect. These permanent defects (YAG pits) can critically affect overall optical quality.
Methods

In this laboratory study, we used the micro-computed tomography (µCT) technique to obtain high-resolution 3D images of the lens and the YAG pits.
Results

To the best of our knowledge, this is the first description of a detailed analysis of IOLs with µCT technology. This non-destructive technique seems to be ideal for comparative studies, measuring dimensions of the damage, and visualizing shooting channels within the material.
Conclusion

µCT is excellently suited to examine an IOL in detail, analyze optics and haptics in three dimensions, and to describe all kinds of changes within the IOL without damaging it.
Originalspracheenglisch
Seiten (von - bis)447-457
Seitenumfang11
FachzeitschriftOphthalmology and Therapy
Jahrgang12
Ausgabenummer1
Frühes Online-Datum12 Dez. 2022
DOIs
PublikationsstatusVeröffentlicht - Feb. 2023

ASJC Scopus subject areas

  • Ophthalmologie

Fields of Expertise

  • Advanced Materials Science

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