Abstract
Steam sterilization processes rely on high heat transfer rates from the steam to the medical devices. To guarantee this, all non-condensable gases (NCGs) must be removed from the steam sterilizer before sterilization. The ratios and distribution of the NCGs in the pre-sterilization phases of both a vacuum and a non-vacuum steam sterilizer are investigated. Two CFD models for simulation of the NCGs in the sterilizers were developed and validated by the measurements of a pressure sensor and eight thermocouples inside the steam sterilizer. Furthermore, a novel method was developed to calculate the real ratio of NCGs based on the standard measurement (EN 13060). The results show that the NCGs ratio defined in the EN 13060 did not accurately represent the real ratios of the NCGs.
Original language | English |
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Pages (from-to) | 502-513 |
Number of pages | 12 |
Journal | Chemie - Ingenieur - Technik |
Volume | 91 |
Issue number | 4 |
Early online date | 21 Jan 2019 |
DOIs | |
Publication status | Published - Apr 2019 |
Keywords
- Autoclaves
- Computational fluid dynamics
- Heat transfer
- Non-condensable gases
- Steam sterilizers
- Wall condensation
ASJC Scopus subject areas
- General Chemical Engineering
- General Chemistry
- Industrial and Manufacturing Engineering