Development of customized 3D printed stainless steel reactors with inline oxygen sensors for aerobic oxidation of Grignard reagents in continuous flow

Manuel Christian Maier; René Lebl; Philipp Sulzer; Josef Lechner; Torsten Mayr; Matej Zadravec; Eyke Slama; Stefan Pfanner; Christoph Schmoelzer; Peter Poechlauer; C. Oliver Kappe; Heidrun Gruber-Wölfler

doi:10.1039/C8RE00278A

Development of customized 3D printed stainless steel reactors with inline oxygen sensors for aerobic oxidation of Grignard reagents in continuous flow

Manuel Christian Maier, René Lebl, Philipp Sulzer, Josef Lechner, Torsten Mayr, Matej Zadravec, Eyke Slama, Stefan Pfanner, Christoph Schmoelzer, Peter Poechlauer, C. Oliver Kappe, Heidrun Gruber-Wölfler

Research output: Contribution to journal › Article › peer-review

Abstract

Additive manufacturing has gained a lot of interest in recent years to create customized reactors and equipment for milli- and micro flow applications. This work presents the development of 3D printed stainless steel reactors for the oxidation of Grignard reagents in flow. In our first approach a 3D printed micro CSTR-cascade was designed as a tool to get more insight in the reaction kinetics. Novel optical sensors were integrated inline in the cascade to monitor the oxygen consumption in real time. Based on the obtained experimental data and CFD simulations, a customized 3D printed split and recombine reactor was designed especially for the needs of the reaction.

Original language	English
Journal	Reaction Chemistry & Engineering
DOIs	https://doi.org/10.1039/C8RE00278A
Publication status	E-pub ahead of print - 2018

Keywords

3D-printing
Grignard oxidation
micro reactor
oxygen sensor

Access to Document

10.1039/C8RE00278A

CC FLOW - Center for Continuous Flow Synthesis and Processing
Mayr, T. (Co-Investigator (CoI)), Gruber-Wölfler, H. (Co-Investigator (CoI)) & Radl, S. (Co-Investigator (CoI))
1/07/17 → 30/06/21
Project: Research project

6th Winter Process Chemistry Conference – Young Chemist Award
Maier, M. C. (Recipient), 9 Dec 2019
Prize: Prizes / Medals / Awards

Cite this

Maier, M. C., Lebl, R., Sulzer, P., Lechner, J., Mayr, T., Zadravec, M., Slama, E., Pfanner, S., Schmoelzer, C., Poechlauer, P., Kappe, C. O., & Gruber-Wölfler, H. (2018). Development of customized 3D printed stainless steel reactors with inline oxygen sensors for aerobic oxidation of Grignard reagents in continuous flow. Reaction Chemistry & Engineering. Advance online publication. https://doi.org/10.1039/C8RE00278A

Maier, MC, Lebl, R, Sulzer, P, Lechner, J, Mayr, T , Zadravec, M , Slama, E, Pfanner, S, Schmoelzer, C, Poechlauer, P, Kappe, CO & Gruber-Wölfler, H 2018, 'Development of customized 3D printed stainless steel reactors with inline oxygen sensors for aerobic oxidation of Grignard reagents in continuous flow', Reaction Chemistry & Engineering. https://doi.org/10.1039/C8RE00278A

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abstract = "Additive manufacturing has gained a lot of interest in recent years to create customized reactors and equipment for milli- and micro flow applications. This work presents the development of 3D printed stainless steel reactors for the oxidation of Grignard reagents in flow. In our first approach a 3D printed micro CSTR-cascade was designed as a tool to get more insight in the reaction kinetics. Novel optical sensors were integrated inline in the cascade to monitor the oxygen consumption in real time. Based on the obtained experimental data and CFD simulations, a customized 3D printed split and recombine reactor was designed especially for the needs of the reaction.",

keywords = "3D-printing, Grignard oxidation, micro reactor, oxygen sensor",

author = "Maier, {Manuel Christian} and Ren{\'e} Lebl and Philipp Sulzer and Josef Lechner and Torsten Mayr and Matej Zadravec and Eyke Slama and Stefan Pfanner and Christoph Schmoelzer and Peter Poechlauer and Kappe, {C. Oliver} and Heidrun Gruber-W{\"o}lfler",

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AU - Maier, Manuel Christian

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AU - Sulzer, Philipp

AU - Lechner, Josef

AU - Mayr, Torsten

AU - Zadravec, Matej

AU - Slama, Eyke

AU - Pfanner, Stefan

AU - Schmoelzer, Christoph

AU - Poechlauer, Peter

AU - Kappe, C. Oliver

AU - Gruber-Wölfler, Heidrun

PY - 2018

Y1 - 2018

N2 - Additive manufacturing has gained a lot of interest in recent years to create customized reactors and equipment for milli- and micro flow applications. This work presents the development of 3D printed stainless steel reactors for the oxidation of Grignard reagents in flow. In our first approach a 3D printed micro CSTR-cascade was designed as a tool to get more insight in the reaction kinetics. Novel optical sensors were integrated inline in the cascade to monitor the oxygen consumption in real time. Based on the obtained experimental data and CFD simulations, a customized 3D printed split and recombine reactor was designed especially for the needs of the reaction.

AB - Additive manufacturing has gained a lot of interest in recent years to create customized reactors and equipment for milli- and micro flow applications. This work presents the development of 3D printed stainless steel reactors for the oxidation of Grignard reagents in flow. In our first approach a 3D printed micro CSTR-cascade was designed as a tool to get more insight in the reaction kinetics. Novel optical sensors were integrated inline in the cascade to monitor the oxygen consumption in real time. Based on the obtained experimental data and CFD simulations, a customized 3D printed split and recombine reactor was designed especially for the needs of the reaction.

KW - 3D-printing

KW - Grignard oxidation

KW - micro reactor

KW - oxygen sensor

U2 - 10.1039/C8RE00278A

DO - 10.1039/C8RE00278A

M3 - Article

SN - 2058-9883

JO - Reaction Chemistry & Engineering

JF - Reaction Chemistry & Engineering

ER -

Development of customized 3D printed stainless steel reactors with inline oxygen sensors for aerobic oxidation of Grignard reagents in continuous flow

Abstract

Keywords

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Projects

CC FLOW - Center for Continuous Flow Synthesis and Processing

Prizes

6th Winter Process Chemistry Conference – Young Chemist Award

Cite this