TY - JOUR
T1 - The need for an integrated multi-OMICs approach in microbiome science in the food system
AU - Ferrocino, Ilario
AU - Rantsiou, Kalliopi
AU - McClure, Ryan
AU - Kostic, Tanja
AU - de Souza, Rafael Soares Correa
AU - Lange, Lene
AU - FitzGerald, Jamie
AU - Kriaa, Aicha
AU - Cotter, Paul
AU - Maguin, Emmanuelle
AU - Schelkle, Bettina
AU - Schloter, Michael
AU - Berg, Gabriele
AU - Sessitsch, Angela
AU - Cocolin, Luca
PY - 2023/3
Y1 - 2023/3
N2 - Microbiome science as an interdisciplinary research field has evolved rapidly over the past two decades, becoming a popular topic not only in the scientific community and among the general public, but also in the food industry due to the growing demand for microbiome-based technologies that provide added-value solutions. Microbiome research has expanded in the context of food systems, strongly driven by methodological advances in different -omics fields that leverage our understanding of microbial diversity and function. However, managing and integrating different complex -omics layers are still challenging. Within the Coordinated Support Action MicrobiomeSupport (https://www.microbiomesupport.eu/), a project supported by the European Commission, the workshop “Metagenomics, Metaproteomics and Metabolomics: the need for data integration in microbiome research” gathered 70 participants from different microbiome research fields relevant to food systems, to discuss challenges in microbiome research and to promote a switch from microbiome-based descriptive studies to functional studies, elucidating the biology and interactive roles of microbiomes in food systems. A combination of technologies is proposed. This will reduce the biases resulting from each individual technology and result in a more comprehensive view of the biological system as a whole. Although combinations of different datasets are still rare, advanced bioinformatics tools and artificial intelligence approaches can contribute to understanding, prediction, and management of the microbiome, thereby providing the basis for the improvement of food quality and safety.
AB - Microbiome science as an interdisciplinary research field has evolved rapidly over the past two decades, becoming a popular topic not only in the scientific community and among the general public, but also in the food industry due to the growing demand for microbiome-based technologies that provide added-value solutions. Microbiome research has expanded in the context of food systems, strongly driven by methodological advances in different -omics fields that leverage our understanding of microbial diversity and function. However, managing and integrating different complex -omics layers are still challenging. Within the Coordinated Support Action MicrobiomeSupport (https://www.microbiomesupport.eu/), a project supported by the European Commission, the workshop “Metagenomics, Metaproteomics and Metabolomics: the need for data integration in microbiome research” gathered 70 participants from different microbiome research fields relevant to food systems, to discuss challenges in microbiome research and to promote a switch from microbiome-based descriptive studies to functional studies, elucidating the biology and interactive roles of microbiomes in food systems. A combination of technologies is proposed. This will reduce the biases resulting from each individual technology and result in a more comprehensive view of the biological system as a whole. Although combinations of different datasets are still rare, advanced bioinformatics tools and artificial intelligence approaches can contribute to understanding, prediction, and management of the microbiome, thereby providing the basis for the improvement of food quality and safety.
KW - food system
KW - metabolomics
KW - metagenomics
KW - metaproteomics
KW - metatranscriptomics
KW - microbiome
KW - Omics integration
UR - http://www.scopus.com/inward/record.url?scp=85146349511&partnerID=8YFLogxK
U2 - 10.1111/1541-4337.13103
DO - 10.1111/1541-4337.13103
M3 - Article
SN - 1541-4337
VL - 22
SP - 1082
EP - 1103
JO - Comprehensive Reviews in Food Science and Food Safety
JF - Comprehensive Reviews in Food Science and Food Safety
IS - 2
ER -