An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues

Anna Pukaluk; Heimo Wolinski; Christian Viertler; Peter Regitnig; Gerhard Holzapfel; Gerhard Sommer

doi:DOI 10.3217/978-3-85125-826-4

An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues

Anna Pukaluk^*, Heimo Wolinski, Christian Viertler, Peter Regitnig, Gerhard Holzapfel, Gerhard Sommer

^*Korrespondierende/r Autor/-in für diese Arbeit

Institut für Biomechanik (7190)

Publikation: Beitrag in Buch/Bericht/Konferenzband › Beitrag in einem Konferenzband › Begutachtung

Abstract

Knowledge of the interaction between the constituents of loaded aortic tissues is crucial to expand our understanding of load-bearing mechanisms in the aorta. We have therefore developed a procedure that enables simultaneous multi-photon microscopy imaging of collagen and elastin in human aortic tissue during the biaxial extension test. The microscopy images obtained were verified with the results of the histological staining. The mechanical response was also compared with findings from previously performed biaxial extension tests. The proposed pipeline has shown successful and has great potential for structural analysis of human aortic tissue.

Originalsprache	englisch
Titel	Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021
Redakteure/-innen	Gernot Müller-Putz, Christian Baumgartner
Erscheinungsort	Graz
Herausgeber (Verlag)	Verlag der Technischen Universität Graz
Seiten	21-24
ISBN (Print)	978-3-85125-826-4
DOIs	https://doi.org/DOI 10.3217/978-3-85125-826-4
Publikationsstatus	Veröffentlicht - 2021
Veranstaltung	Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021 - Graz, Österreich Dauer: 30 Sept. 2021 → 1 Okt. 2021

Konferenz

Konferenz	Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021
Land/Gebiet	Österreich
Ort	Graz
Zeitraum	30/09/21 → 1/10/21

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DOI 10.3217/978-3-85125-826-4Lizenz: CC BY 4.0

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Pukaluk, A., Wolinski, H., Viertler, C., Regitnig, P., Holzapfel, G., & Sommer, G. (2021). An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues. in G. Müller-Putz, & C. Baumgartner (Hrsg.), Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021 (S. 21-24). Verlag der Technischen Universität Graz. https://doi.org/DOI 10.3217/978-3-85125-826-4

An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues. / Pukaluk, Anna; Wolinski, Heimo; Viertler, Christian et al.
Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021. Hrsg. / Gernot Müller-Putz; Christian Baumgartner. Graz: Verlag der Technischen Universität Graz, 2021. S. 21-24.

Publikation: Beitrag in Buch/Bericht/Konferenzband › Beitrag in einem Konferenzband › Begutachtung

Pukaluk, A, Wolinski, H, Viertler, C, Regitnig, P, Holzapfel, G & Sommer, G 2021, An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues. in G Müller-Putz & C Baumgartner (Hrsg.), Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021. Verlag der Technischen Universität Graz, Graz, S. 21-24, Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021, Graz, Österreich, 30/09/21. https://doi.org/DOI 10.3217/978-3-85125-826-4

Pukaluk A, Wolinski H, Viertler C, Regitnig P, Holzapfel G , Sommer G. An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues. in Müller-Putz G, Baumgartner C, Hrsg., Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021. Graz: Verlag der Technischen Universität Graz. 2021. S. 21-24 doi: DOI 10.3217/978-3-85125-826-4

Pukaluk, Anna ; Wolinski, Heimo ; Viertler, Christian et al. / An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues. Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021. Hrsg. / Gernot Müller-Putz ; Christian Baumgartner. Graz : Verlag der Technischen Universität Graz, 2021. S. 21-24

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title = "An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues",

abstract = "Knowledge of the interaction between the constituents of loaded aortic tissues is crucial to expand our understanding of load-bearing mechanisms in the aorta. We have therefore developed a procedure that enables simultaneous multi-photon microscopy imaging of collagen and elastin in human aortic tissue during the biaxial extension test. The microscopy images obtained were verified with the results of the histological staining. The mechanical response was also compared with findings from previously performed biaxial extension tests. The proposed pipeline has shown successful and has great potential for structural analysis of human aortic tissue.",

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T1 - An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues

AU - Pukaluk, Anna

AU - Wolinski, Heimo

AU - Viertler, Christian

AU - Regitnig, Peter

AU - Holzapfel, Gerhard

AU - Sommer, Gerhard

PY - 2021

Y1 - 2021

N2 - Knowledge of the interaction between the constituents of loaded aortic tissues is crucial to expand our understanding of load-bearing mechanisms in the aorta. We have therefore developed a procedure that enables simultaneous multi-photon microscopy imaging of collagen and elastin in human aortic tissue during the biaxial extension test. The microscopy images obtained were verified with the results of the histological staining. The mechanical response was also compared with findings from previously performed biaxial extension tests. The proposed pipeline has shown successful and has great potential for structural analysis of human aortic tissue.

AB - Knowledge of the interaction between the constituents of loaded aortic tissues is crucial to expand our understanding of load-bearing mechanisms in the aorta. We have therefore developed a procedure that enables simultaneous multi-photon microscopy imaging of collagen and elastin in human aortic tissue during the biaxial extension test. The microscopy images obtained were verified with the results of the histological staining. The mechanical response was also compared with findings from previously performed biaxial extension tests. The proposed pipeline has shown successful and has great potential for structural analysis of human aortic tissue.

KW - human aorta

KW - collagen

KW - elastin

KW - biaxial extension test

KW - multi-photon microscopy

U2 - DOI 10.3217/978-3-85125-826-4

DO - DOI 10.3217/978-3-85125-826-4

M3 - Conference paper

SN - 978-3-85125-826-4

SP - 21

EP - 24

BT - Proceedings of the Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021

A2 - Müller-Putz, Gernot

A2 - Baumgartner, Christian

PB - Verlag der Technischen Universität Graz

CY - Graz

T2 - Annual Meeting of the Austrian Society for Biomedical Engineering ÖGBMT2021

Y2 - 30 September 2021 through 1 October 2021

ER -

An approach for visualization of the interaction between collagen and elastin in loaded human aortic tissues

Abstract

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