Improving the accuracy of Multipool-Lorentzian fitting in CEST MRI by use of a Pseudo-Voigt lineshape for direct water saturation

Huemer, M. (Speaker)
Stilianu, C. (Contributor)
Stollberger, R. (Contributor)

Institute of Biomedical Imaging (7170)

Activity: Talk or presentation › Poster presentation › Science to science

Description

In Chemical Exchange Saturation Transfer (CEST) MRI one common analysis technique is Multipool-Lorentzian fitting of the resulting Z-Spectrum. Multiple Lorentzian lineshapes are fitted to the measured data. The lineshape of the direct water saturation (DS) can deviate substantially from a Lorentzian depending on the saturation scheme and B1. To prevent a cross-influence of the DS on the CEST and increase the fit accuracy we propose the use of a Pseudo-Voigt lineshape for the water line.

Period	6 Jun 2023
Event title	ISMRM & ISMRT Annual Meeting & Exhibition 2023
Event type	Conference
Location	Toronto, CanadaShow on map
Degree of Recognition	International