Abstract
There is evidence on body fluid volume effects of head-down tilt bed rest [1] and altered oral sodium supply [2,3], but the combined impact of both has not been investigated in detail. We therefore studied circulatory adaptation to 8 days -6° head down bed rest (HDBR) with different levels (≈140 to ≈430 mM/d) of oral sodium load (SL). We expected decreased extracellular volume and increased aldosterone and PRA levels with low sodium load, and hypothesized that these effects get exaggerated with additional HDBR, also influencing lower body suction (LBNP) responses. Variations in sodium status seem to influence plasma but not interstitial volume, confirming recent results of another group who used different experimental conditions [3].
Original language | English |
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Pages (from-to) | 205-206 |
Number of pages | 2 |
Journal | European Space Agency, (Special Publication) ESA SP |
Issue number | 501 |
Publication status | Published - 1 Sept 2002 |
Event | Proceedings of the European Symposium on Life in Space for Life on Earth - Stockholm, Sweden Duration: 2 Jun 2002 → 7 Jun 2002 |
ASJC Scopus subject areas
- Aerospace Engineering
- Space and Planetary Science